Course Title: Assessing Exposure to Chemicals in Consumer Products for Alternatives Assessment, Life Cycle Assessment, and High-throughput Risk Screening – The Product Intake Fraction Framework Theory and Practical Examples
Course Summary: To meet the increasing need for assessing exposure to chemicals in consumer products for life cycle assessment (LCA), chemical alternatives assessment (CAA), and high throughput risk-based screening (HTS), this course provides a practical overview of the mass-balance based tools to assess multi-pathway human exposure to chemicals in consumer products, and how to integrate this with health effects modelling based on comparative and quantitative metrics. We will illustrate how consumer exposure can be integrated into LCA, CAA, and HTS studies. We then guide the participants through examples developing exposure and impact factors for various consumers, exposure scenarios using a matrix-based modelling framework that is aligned in its approach with the UNEP/SETAC scientific consensus model USEtox® for characterizing human toxicity and ecotoxicity impacts. We will conclude with a demonstration of how this framework fills in important gaps in current assessments and how it can be used in various science-policy fields, including the prioritization and ranking of chemicals, chemical substitution and life cycle toxicity characterization. 

  Modules include:
  • Session 1:  Consumer exposure in different contexts: Product intake fraction and exposure matrix framework
  • Session 2:  Data and models for detergents, building materials, food contact materials and personal care products
  • Session 3:  Consumer exposure in alternatives assessments and life cycle analysis
  • Session 4:  Consumer exposure in risk-based screening assessments

All course attendees should bring laptops equipped with MS Excel (macro-enabled) software. 

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